Article
Regulation of UmuD cleavage: role of the amino-terminal tail.
Journal of molecular biology - 2 Oct 1998
McDonald J P, Maury E E, Levine A S, Woodgate R
Abstract excerpt
An essential step in SOS mutagenesis is the RecA-mediated posttranslational processing of UmuD-like proteins to the shorter, but mutagenically active, UmuD'-like proteins. Interestingly, the UmuD-like proteins undergo posttranslational processing at different rates. For example, although the Esch...
Topics
- Amino Acid Sequence
- Amino Acid Substitution
- Bacterial Proteins
- Binding Sites
- Conserved Sequence
- DNA-Directed DNA Polymerase
- Escherichia coli
- Escherichia coli Proteins
- Half-Life
- Hydrogen-Ion Concentration
- Kinetics
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Proline
- Protein Binding
- Protein Processing, Post-Translational
- Rec A Recombinases