Article
The UmuD' protein filament and its potential role in damage induced mutagenesis.
Structure (London, England : 1993) - 15 Dec 1996
Peat T S, Frank E G, McDonald J P, Levine A S, Woodgate R, Hendrickson W A
Abstract excerpt
BACKGROUND: Damage induced 'SOS mutagenesis' may occur transiently as part of the global SOS response to DNA damage in bacteria. A key participant in this process is the UmuD protein, which is produced in an inactive from but converted to the active form, UmuD', by a RecA-mediated self-cleavage reaction. UmuD', together with UmuC and activated RecA (RecA*), enables the DNA polymerase III holoenzyme to replicate...
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