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Article

Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.

Journal of bacteriology - 1 Jan 1999

Ohta T, Sutton M D, Guzzo A, Cole S, Ferentz A E, Walker G C

Abstract excerpt

The products of the SOS-regulated umuDC operon are required for most UV and chemical mutagenesis in Escherichia coli, a process that results from a translesion synthesis mechanism. The UmuD protein is activated for its role in mutagenesis by a RecA-facilitated autodigestion that removes the N-ter...

Topics

Bacterial Proteins
DNA-Directed DNA Polymerase
Dimerization
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Methyl Methanesulfonate
Models, Molecular
Mutagenesis
Mutation
Operon
Point Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Conformation

SOS Response, Genetics

Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 9864328
DOI: 10.1128/JB.181.1.177-185.1999
PMCID: PMC103547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9864328-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.PMID 9864328Read ↗

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Novel Escherichia coli umuD' mutants: structure-function insights into SOS mutagenesis.Semantic proximity Read ↗

Escherichia coli umuDC mutants: DNA sequence alterations and UmuD cleavage.Semantic proximity Read ↗

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