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Article

Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.

Journal of bacteriology - 1 Jan 1999

Ohta T, Sutton M D, Guzzo A, Cole S, Ferentz A E, Walker G C

Abstract excerpt

The products of the SOS-regulated umuDC operon are required for most UV and chemical mutagenesis in Escherichia coli, a process that results from a translesion synthesis mechanism. The UmuD protein is activated for its role in mutagenesis by a RecA-facilitated autodigestion that removes the N-terminal 24 amino acids. A previous genetic screen for nonmutable umuD mutants had resulted in the isolation of a set of...

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Identifiers

PMID: 9864328
DOI: 10.1128/JB.181.1.177-185.1999
PMCID: PMC103547

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.PMID 9864328Read ↗

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