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Article

Intermolecular cleavage by UmuD-like enzymes: identification of residues required for cleavage and substrate specificity.

Journal of molecular biology - 5 Feb 1999

McDonald J P, Peat T S, Levine A S, Woodgate R

Abstract excerpt

The UmuD-like proteins are best characterized for their role in damage-induced SOS mutagenesis. An essential step in this process is the enzymatic self-processing of the UmuD-like proteins. This reaction is thought to occur either via an intramolecular or intermolecular self-cleavage mechanism. Here, we demonstrate that it can also occur via an heterologous intermolecular cleavage reaction. The Escherichia coli...

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Identifiers

PMID: 9925794
DOI: 10.1006/jmbi.1998.2433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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