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Article

Proteolytic activation of UmuD and MucA proteins for SOS mutagenesis.

Basic life sciences - 1 Jan 1990

Shiba T, Iwasaki H, Nakata A, Shinagawa H

Abstract excerpt

SOS mutagenesis in Escherichia coli requires the functions of the umuD, C genes, or their functional analogues mucA, B derived from a plasmid pKM101, and the recA gene. However, mere derepression of these SOS genes does not increase the ability of the cell to perform mutagenesis. Activation of RecA protein to a form (RecA*) that mediates cleavage of the LexA repressor is required for mutagenesis. We present...

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Identifiers

PMID: 2183775
DOI: 10.1007/978-1-4615-9561-8_31

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Proteolytic activation of UmuD and MucA proteins for SOS mutagenesis.PMID 2183775Read ↗

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Requirements for bypass of UV-induced lesions in single-stranded DNA of bacteriophage phi X174 in Salmonella typhimurium.Semantic proximity Read ↗

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Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.Semantic proximity Read ↗

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