Proteolytic activation of UmuD and MucA proteins for SOS mutagenesis.

doi:10.1007/978-1-4615-9561-8_31

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Article

Proteolytic activation of UmuD and MucA proteins for SOS mutagenesis.

Basic life sciences - 1 Jan 1990

Shiba T, Iwasaki H, Nakata A, Shinagawa H

Abstract excerpt

SOS mutagenesis in Escherichia coli requires the functions of the umuD, C genes, or their functional analogues mucA, B derived from a plasmid pKM101, and the recA gene. However, mere derepression of these SOS genes does not increase the ability of the cell to perform mutagenesis. Activation of Re...

Topics

Bacterial Proteins
DNA Damage
DNA Repair
DNA-Directed DNA Polymerase
Enzyme Activation
Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Mutation
Protein Processing, Post-Translational
Rec A Recombinases
Serine Endopeptidases

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