Article
Genetic analyses of cellular functions required for UV mutagenesis in Escherichia coli.
Basic life sciences - 1 Jan 1990
Battista J R, Nohmi T, Donnelly C E, Walker G C
Abstract excerpt
In Escherichia coli, most UV and chemical mutagenesis is not a passive process and requires the participation of the umuD and umuC gene products. However, the molecular mechanism of UV mutagenesis is not yet understood and the roles of the UmuD and UmuC proteins have not been elucidated. The umuDC operon is induced by UV irradiation and regulated as part of the SOS response. Genetic evidence now indicates that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
