Genetic analyses of cellular functions required for UV mutagenesis in Escherichia coli.

doi:10.1007/978-1-4615-9561-8_22

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Article

Genetic analyses of cellular functions required for UV mutagenesis in Escherichia coli.

Basic life sciences - 1 Jan 1990

Battista J R, Nohmi T, Donnelly C E, Walker G C

Abstract excerpt

In Escherichia coli, most UV and chemical mutagenesis is not a passive process and requires the participation of the umuD and umuC gene products. However, the molecular mechanism of UV mutagenesis is not yet understood and the roles of the UmuD and UmuC proteins have not been elucidated. The umuD...

Topics

Bacterial Proteins
Coliphages
DNA Damage
DNA Repair
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Mutation
Ultraviolet Rays
Viral Proteins

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