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Article

Specific RecA amino acid changes affect RecA-UmuD'C interaction.

Molecular microbiology - 1 Apr 1998

Sommer S, Boudsocq F, Devoret R, Bailone A

Abstract excerpt

The UmuD'C mutagenesis complex accumulates slowly and parsimoniously after a 12 Jm(-2) UV flash to attain after 45 min a low cell concentration between 15 and 60 complexes. Meanwhile, RecA monomers go up to 72,000 monomers. By contrast, when the UmuD'C complex is constitutively produced at a high concentration, it inhibits recombinational repair and then markedly reduces bacterial survival from DNA damage. We...

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Source

Identifiers

PMID: 9622353
DOI: 10.1046/j.1365-2958.1998.00803.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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