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Article

Novel Escherichia coli umuD' mutants: structure-function insights into SOS mutagenesis.

Journal of bacteriology - 1 Sept 1998

McLenigan M, Peat T S, Frank E G, McDonald J P, Gonzalez M, Levine A S, Hendrickson W A, Woodgate R

Abstract excerpt

Although it has been 10 years since the discovery that the Escherichia coli UmuD protein undergoes a RecA-mediated cleavage reaction to generate mutagenically active UmuD', the function of UmuD' has yet to be determined. In an attempt to elucidate the role of UmuD' in SOS mutagenesis, we have utilized a colorimetric papillation assay to screen for mutants of a hydroxylamine-treated, low-copy-number umuD' plasmid...

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Source

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Identifiers

PMID: 9721309
DOI: 10.1128/JB.180.17.4658-4666.1998
PMCID: PMC107481

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Source receipt: pubmed, retrieved 7 Sept 2026.

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