Abnormal change of p53 gene in gastric and precancerous lesions and APC gene deletion in gastric carcinoma and near tissues.

doi:10.1007/BF02888238

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Article

Abnormal change of p53 gene in gastric and precancerous lesions and APC gene deletion in gastric carcinoma and near tissues.

Journal of Tongji Medical University = Tong ji yi ke da xue xue bao - 1 Jan 1997

Hao Y, Zhang J, Yi C, Qian W

Abstract excerpt

p53 gene mutation (exon4, 5, 6, 7, 8 and intron6) in gastric cancer and precancerous lesions and p53 gene (exon4 and ontron6), APC gene deletion in gastric carcinomas were studied by PCR/SSCP and PCR/RFLP. Results showed mutation rate of p53 in metaplasia, dysplasia and gastric carcinoma was 37.5...

Topics

Gastric Mucosa
Gastritis
Gene Deletion
Genes, APC
Genes, p53
Humans
Loss of Heterozygosity
Metaplasia
Mutation
Precancerous Conditions
Stomach Neoplasms

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