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Article

[Expression and mutation of p53 and H-ras genes in the carcinogenesis and development of gastric adenocarcinoma induced by MNNG in rats].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Apr 1998

Meng Z, Lei D, Wang J

Abstract excerpt

OBJECTIVE: To investigate the effect of p53 and H-ras genes in the carcinogenesis of and development of gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in Wistar rats. METHODS: The expression of p53 and H-ras genes in normal mucosa, precancerous lesions and induced-cancers were studied immunohistochemically. DNA isolated from the precancerous lesion and tumors were analysed by PCR-SSCP for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11244961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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