Article
Mutations of p53 gene in gastric carcinoma in Taiwan.
Anticancer research - 1 Jan 2000
Wang J Y, Lin S R, Hsieh J S, Hsu C H, Huang Y S, Huang T J
Abstract excerpt
BACKGROUND: p53 gene mutation and p53 protein accumulation is the most common event in human cancers. The present study was conducted to investigate the occurrence of p53 mutations in patients with gastric carcinoma in Taiwan. MATERIALS AND METHODS: Tumor samples from 36 patients with primary gastric carcinoma undergoing radical gastrectomy were evaluated. The mutational status of the p53 (exons 5 to 8) was...
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