Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2011

Chen Han-Chun, Chen Hui-Juan, Khan Md Asaduzzaman, Rao Zhou-Zhou, Wan Xin-Xing, Tan Bo, Zhang Dian-Zheng

Abstract excerpt

This case-control study investigated the mutations in p53 and k-ras genes of 123 gastric carcinoma patients and 129 normal individuals from Hunan, China. By isolating genomic DNA from peripheral blood and employing polymerase chain reaction-single strand conformation polymorphism and DNA sequencing, the mutations of p53 exons-5, 6, 7, and 8 and k-ras were detected. The overall mutation frequency of p53 was 29.3%,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Codon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Frameshift Mutation

Share to Genes, p53

Share to Genes, ras

Share to Point Mutation

Share to Stomach Neoplasms

Source

Identifiers

PMID: 21080251
DOI: 10.1007/s13277-010-0129-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China.PMID 21080251Read ↗

P53, p21, and p73 gene polymorphisms in gastric carcinoma.Semantic proximity Read ↗

P53 mutations in colorectal cancer from northern Iran: Relationships with site of tumor origin, microsatellite instability and K-ras mutations.Semantic proximity Read ↗

Mutations of p53 gene in gastric carcinoma in Taiwan.Semantic proximity Read ↗

K-ras and p53 gene mutations in colorectal cancer in 57 Japanese patients.Semantic proximity Read ↗

p53 Gene mutations in sporadic colorectal carcinoma in Guangxi region.Semantic proximity Read ↗

Mutations of p53 in gallbladder carcinomas in high-incidence areas of Japan and Chile.Semantic proximity Read ↗

Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy.Semantic proximity Read ↗

Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area.Semantic proximity Read ↗

p53 mutations in esophageal tumors from high-incidence areas of China.Semantic proximity Read ↗

Non-CpG sites preference in G:C > A:T transition of TP53 in gastric cancer of Eastern Europe (Poland, Romania and Hungary) compared to East Asian countries (China and Japan)Semantic proximity Read ↗

Alterations in K-ras, APC and p53-multiple genetic pathway in colorectal cancer among Indians.Semantic proximity Read ↗

[Research advances of K-ras mutation in the prognosis and targeted therapy of gastric cancer].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.