[Mutations of the p53 suppressor gene in gastric adenocarcinoma].

Article

[Mutations of the p53 suppressor gene in gastric adenocarcinoma].

Revista medica de Chile - 1 May 1998

Aranda M, Náquira N, Karque R, Mendoza H, Sepúlveda C, Silva C

Abstract excerpt

BACKGROUND: We have shown numeric alterations such as hyperploidy and hypoploidy with loss of chromosome 17 in primary gastric cancer. This chromosome maps p53 suppressor gene that induces the transcription of genes related to cellular cycle control, DNA synthesis and repair, cellular differentia...

Topics

Adenocarcinoma
Adult
Aged
DNA Mutational Analysis
Female
Gastric Mucosa
Genes, p53
Humans
Male
Middle Aged
Mutation
Stomach Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.