Article
Discrimination of p53 immunohistochemistry-positive tumors by its staining pattern in gastric cancer.
Cancer medicine - 1 Jan 2015
Ando Koji, Oki Eiji, Saeki Hiroshi, Yan Zhao, Tsuda Yasuo, Hidaka Gen, Kasagi Yuta, Otsu Hajime, Kawano Hiroyuki, Kitao Hiroyuki, Morita Masaru, Maehara Yoshihiko
Abstract excerpt
Immunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function of p53. However, there are some discrepancies between the result of immunohistochemistry staining and mutation analysis. This study attempted to find a new definition of p53 staining by its staining pattern. Immunohistochemistry staining of p53 and TP53 gene mutation analysis were performed in 148 gastric cancer...
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