p53 gene mutations in gastric and esophageal cancers.

doi:10.1016/0016-5085(92)90022-q

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Article

p53 gene mutations in gastric and esophageal cancers.

Gastroenterology - 1 Sept 1992

Imazeki F, Omata M, Nose H, Ohto M, Isono K

Abstract excerpt

The presence of point mutation of the p53 gene in exons 5, 6, 7, and 8 was examined in 10 cases of gastric adenocarcinoma and 5 cases of esophageal squamous cell carcinoma by polymerase chain reaction and direct nucleotide sequencing. Mutations of the p53 gene were found in 5 cases of gastric can...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Esophageal Neoplasms
Female
Genes, p53
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Stomach Neoplasms

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