Article
Contributions of the TATA box sequence to rate-limiting steps in transcription initiation by RNA polymerase II.
Journal of molecular biology - 17 Apr 1998
Hoopes B C, LeBlanc J F, Hawley D K
Abstract excerpt
We have examined the role of the TATA box in determining transcription initiation frequency in vitro by studying a collection of promoters containing different TATA sequences in the context of the adenovirus major late promoter. In addition to measuring transcription rates, we have determined how...
Topics
- Adenoviridae
- DNA Footprinting
- DNA-Binding Proteins
- Kinetics
- Mutation
- Promoter Regions, Genetic
- Protein Binding
- RNA Polymerase II
- Ribonuclease T1
- TATA Box
- TATA-Box Binding Protein
- Thermodynamics
- Transcription Factors
- Transcription, Genetic
- Transcriptional Activation
- Viral Proteins