Article
The initiator element of the adenovirus major late promoter has an important role in transcription initiation in vivo.
Journal of virology - 1 Jan 1997
Lu H, Reach M D, Minaya E, Young C S
Abstract excerpt
Previous results showed that the structure and function of the adenovirus major late promoter (MLP) can be analyzed genetically in its correct location, despite its essential role in the viral life cycle. This genetic approach was extended to investigate the in vivo role of the initiator (INR), a...
Topics
- Adenoviridae
- Codon, Initiator
- DNA, Viral
- Defective Viruses
- Humans
- Mutagenesis
- Peptide Chain Initiation, Translational
- Phenotype
- Promoter Regions, Genetic
- RNA, Viral
- Regulatory Sequences, Nucleic Acid
- TATA Box
- Transcription, Genetic
- Tumor Cells, Cultured
- Virus Replication