Promoter activity and distance constraints of one versus two Sp1 binding sites.

Article

Promoter activity and distance constraints of one versus two Sp1 binding sites.

The Journal of biological chemistry - 25 Oct 1991

Segal R, Berk A J

Abstract excerpt

In the simple adenovirus 2 early 1B (E1B) promoter, moving the single Sp1 transcription factor binding site (GC box) from its wild-type position eight base pairs (bp) from the TATA box to 30 bp upstream is equivalent to its deletion (Wu, L., and Berk, A. (1988) Genes & Dev. 2, 403-411). In more c...

Topics

Adenoviridae
Base Sequence
Binding Sites
Genes, Viral
HeLa Cells
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Promoter Regions, Genetic
RNA, Viral
Sp1 Transcription Factor
TATA Box
Transcription, Genetic

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