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Article

TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters.

Genes & development - 1 Feb 1992

Colgan J, Manley J L

Abstract excerpt

We have studied the effect of exogenous expression of the basal transcription factor TFIID on the activities of several different TATA-containing and TATA-lacking promoters. Overexpression of TFIID from a transfected plasmid in Drosophila Schneider cells resulted in substantial concentration-dependent increases in expression from a cotransfected minimal TATA-containing promoter. Overexpression of TFIID activated...

Topics

Animals
Blotting, Western
Chloramphenicol O-Acetyltransferase
Drosophila
Gene Expression Regulation
Heat-Shock Proteins
Mutation
Promoter Regions, Genetic
RNA Polymerase II
Recombinant Fusion Proteins
TATA Box

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factor TFIID

Transcription Factors

Transcription, Genetic

beta-Galactosidase

Source

Identifiers

PMID: 1737620
DOI: 10.1101/gad.6.2.304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1737620-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters.PMID 1737620Read ↗

Mechanistic Differences in Transcription Initiation at TATA-Less and TATA-Containing Promoters.Semantic proximity Read ↗

Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro.Semantic proximity Read ↗

Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.Semantic proximity Read ↗

Vertebrate TBP-like protein (TLP/TRF2/TLF) stimulates TATA-less terminal deoxynucleotidyl transferase promoters in a transient reporter assay, and TFIIA-binding capacity of TLP is required for this function.Semantic proximity Read ↗

Direct recognition of initiator elements by a component of the transcription factor IID complex.Semantic proximity Read ↗

TBP-associated factors are not generally required for transcriptional activation in yeast.Semantic proximity Read ↗

The Drosophila TATA binding protein contains a strong but masked activation domain.Semantic proximity Read ↗

TATA sequence requirements for the initiation of transcription for an RNA polymerase II in vitro transcription system from Nicotiana tabacum.Semantic proximity Read ↗

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Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.Semantic proximity Read ↗

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