Article
Spacing requirements for simultaneous recognition of the adenovirus major late promoter TATAAAAG box and initiator element.
Archives of biochemistry and biophysics - 15 Mar 2005
Ren Delin, Nedialkov Yuri A, Li Fang, Xu Dianpeng, Reimers Stephan, Finkelstein Ann, Burton Zachary F
Abstract excerpt
The distance between the TATAAAAG box and initiator element of the strong adenovirus major late promoter was systematically altered to determine the optimal spacing for simultaneous recognition of both elements. We find that the TATAAAAG element is strongly dominant over the initiator for specification of the start site. The wild type spacing of 23 base pairs between TATAAAAG and +1A is optimal for promoter...
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