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Article

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter.

Nature - 1 Jan 2000

Wu L, Rosser D S, Schmidt M C, Berk A

Abstract excerpt

Adenovirus E1A proteins stimulate transcription by RNA polymerases II and III from many promoters. The detailed mechanism of transcriptional activation (transactivation) by E1A proteins remains unclear, but genetic and biochemical results suggest that E1A products might act to stimulate the activity of cellular transcription factors. In this study, a detailed mutational analysis of the adenovirus E1B promoter was...

Topics

Adenovirus Early Proteins
Adenoviruses, Human
Base Sequence
Chromosome Deletion
Genes
Genes, Viral
Mutation
Oncogene Proteins, Viral
Promoter Regions, Genetic
Transcription, Genetic

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Identifiers

PMID: 2951598
DOI: 10.1038/326512a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2951598-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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