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Article

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor.

Cell - 18 Oct 1991

Lee W S, Kao C C, Bryant G O, Liu X, Berk A J

Abstract excerpt

The adenovirus large E1A protein is a potent activator of transcription. We use several different experimental approaches to demonstrate that the large E1A protein binds specifically and stably to the TATA box-binding factor (TFIID), the general polymerase II transcription factor that initiates assembly of transcription complexes. Sedimentation velocity centrifugation revealed that TFIID and E1A form a...

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Identifiers

PMID: 1833071
DOI: 10.1016/0092-8674(91)90188-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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