Article
Mechanism of initiator-mediated transcription: evidence for a functional interaction between the TATA-binding protein and DNA in the absence of a specific recognition sequence.
Molecular and cellular biology - 1 Jul 1993
Zenzie-Gregory B, Khachi A, Garraway I P, Smale S T
Abstract excerpt
Promoters containing Sp1 binding sites and an initiator element but lacking a TATA box direct high levels of accurate transcription initiation by using a mechanism that requires the TATA-binding protein (TBP). We have begun to address the role of TBP during transcription from Sp1-initiator promot...
Topics
- Base Sequence
- DNA
- DNA-Binding Proteins
- Genetic Variation
- Humans
- Molecular Sequence Data
- Plasmids
- Promoter Regions, Genetic
- TATA-Box Binding Protein
- Transcription Factors
- Transcription, Genetic
- Transfection