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Article

Probing functional interfaces of rod PDE gamma-subunit using scanning fluorescent labeling.

Cell biochemistry and biophysics - 1 Jan 1998

Granovsky A E, McEntaffer R, Artemyev N O

Abstract excerpt

In the dark, the activity of the rod cGMP phosphodiesterase (PDE) catalytic alpha- and beta-subunits (P alpha beta) is inhibited by two gamma-subunits (P gamma). On light stimulation of the photoreceptor cells, the GTP-bound alpha-subunit of visual G-protein transducin (GtaGTP) displaces the P gamma-subunits from their inhibitory sites on P alpha beta, leading to the effect or enzyme activation. We designed a...

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PMID: 9515163
DOI: 10.1007/BF02737808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Probing functional interfaces of rod PDE gamma-subunit using scanning fluorescent labeling.PMID 9515163Read ↗

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