Article
Photoreceptor guanylate cyclase variants: cGMP production under control.
Acta biochimica Polonica - 1 Jan 2003
Sokal Izabela, Alekseev Andrei, Palczewski Krzysztof
Abstract excerpt
Changes in the Ca2+ concentration are thought to affect many processes, including signal transduction in a vast number of biological systems. However, only in few cases the molecular mechanisms by which Ca2+ mediates its action are as well understood as in phototransduction. In dark-adapted photoreceptor cells, the equilibrium level of cGMP is maintained by two opposing activities, such as phosphodiesterase (PDE)...
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