Article
Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin.
Science (New York, N.Y.) - 17 Jan 1997
Onrust R, Herzmark P, Chi P, Garcia P D, Lichtarge O, Kingsley C, Bourne H R
Abstract excerpt
Transmembrane receptors for hormones, neurotransmitters, light, and odorants mediate their cellular effects by activating heterotrimeric guanine nucleotide-binding proteins (G proteins). Crystal structures have revealed contact surfaces between G protein subunits, but not the surfaces or molecula...
Topics
- Aluminum Compounds
- Animals
- Binding Sites
- COS Cells
- Fluorides
- Guanosine 5'-O-(3-Thiotriphosphate)
- Guanosine Diphosphate
- Models, Molecular
- Mutation
- Phenotype
- Protein Conformation
- Retinaldehyde
- Rhodopsin
- Rod Cell Outer Segment
- Transducin