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Article

A novel strategy to engineer functional fluorescent inhibitory G-protein alpha subunits.

The Journal of biological chemistry - 9 Aug 2002

Leaney Joanne L, Benians Amy, Graves Fiona M, Tinker Andrew

Abstract excerpt

Signaling studies in living cells would be greatly facilitated by the development of functional fluorescently tagged G-protein alpha subunits. We have designed G(i/o)alpha subunits fused to the cyan fluorescent protein and assayed their function by studying the following two signal transduction pathways: the regulation of G-protein-gated inwardly rectifying K(+) channels (Kir3.0 family) and adenylate cyclase....

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Source

Identifiers

PMID: 12048213
DOI: 10.1074/jbc.M204683200

Genes

GAP43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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