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Article

Marker selection for the transmission/disequilibrium test, in recently admixed populations.

American journal of human genetics - 1 Mar 1998

Kaplan N L, Martin E R, Morris R W, Weir B S

Abstract excerpt

Recent admixture between genetically differentiated populations can result in high levels of association between alleles at loci that are <=10 cM apart. The transmission/disequilibrium test (TDT) proposed by Spielman et al. (1993) can be a powerful test of linkage between disease and marker loci in the presence of association and therefore could be a useful test of linkage in admixed populations. The degree of...

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PMID: 9497257
DOI: 10.1086/301760
PMCID: PMC1376954

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