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Article

Linkage disequilibrium in admixed populations: applications in gene mapping.

The Journal of heredity - 1 Jan 2000

Briscoe D, Stephens J C, O'Brien S J

Abstract excerpt

A method to detect linkage of genetic traits to polymorphic DNA markers in outbred populations when pedigree analysis is not feasible is presented. The procedure takes advantage of increased linkage disequilibrium that occurs when isolated races or subspecies mate and interbreed. By selecting restriction fragment length polymorphism (RFLP) or microsatellite marker loci that have different allele frequencies in...

Topics

Alleles
Animals
Chromosome Mapping
DNA
Gene Frequency
Genetic Markers
Humans
Linkage Disequilibrium
Models, Genetic
Pedigree
Polymorphism, Genetic

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PMID: 8120361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8120361-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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