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Article

Simple approximations for the maximal transmission/disequilibrium test with a multi-allelic marker.

Annals of human genetics - 1 Nov 2000

Betensky R A, Rabinowitz D

Abstract excerpt

Spielman et al. (1993) popularized the transmission/disequilibrium test (TDT) to test for linkage between disease and marker loci that show a population association. Several authors have proposed extensions to the TDT for multi-allelic markers. Many of these approaches exhibit a 'swamping' effect in which a marker with a strong effect is not detected by a global test that includes many markers with no effect. To...

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Identifiers

PMID: 11281219
DOI: 10.1046/j.1469-1809.2000.6460567.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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