An extended transmission/disequilibrium test (TDT) for multi-allele marker loci.

doi:10.1111/j.1469-1809.1995.tb00751.x

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Article

An extended transmission/disequilibrium test (TDT) for multi-allele marker loci.

Annals of human genetics - 1 Jul 1995

Sham P C, Curtis D

Abstract excerpt

The transmission/disequilibrium test (TDT) was recently introduced by Spielman et al. (1993) as a test for linkage and linkage disequilibrium. The test is based on the unequal probability of transmission of two different marker alleles from parents to affected offspring, when the marker locus and...

Topics

Alleles
Genetic Markers
Genotype
Humans
Linkage Disequilibrium

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