Article
An extended transmission/disequilibrium test (TDT) for multi-allele marker loci.
Annals of human genetics - 1 Jul 1995
Sham P C, Curtis D
Abstract excerpt
The transmission/disequilibrium test (TDT) was recently introduced by Spielman et al. (1993) as a test for linkage and linkage disequilibrium. The test is based on the unequal probability of transmission of two different marker alleles from parents to affected offspring, when the marker locus and the hypothetical disease locus are linked and are in linkage disequilibrium. The probabilities of marker allele...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.