Article
Power of transmission/disequilibrium tests in admixed populations.
Genetic epidemiology - 1 Jul 2008
Li Miao-Xin, Jiang Lin, Song You-Qiang, Sham Pak C
Abstract excerpt
The power of transmission/disequilibrium tests (TDTs) for detecting disease susceptibility loci is expected to be influenced by population admixture through its impact on the degree of linkage disequilibrium (LD) between the genetic marker and the DSL. However, few studies have been done to systematically examine this behavior of the TDTs in admixed populations. In the present study, extensive computer...
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