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Article

Linking Frizzled and Wnt signaling in Drosophila development.

Development (Cambridge, England) - 1 Nov 1997

Tomlinson A, Strapps W R, Heemskerk J

Abstract excerpt

Drosophila Frizzled-2 (Dfz2) has been identified as a putative fly Wingless (Wg) receptor. Although Dfz2 shows significant homology with Fz, a protein that operates in the mechanisms that establish planar polarity in Drosophila epithelia, any clear evidence for an involvement by Fz in a Wnt signaling pathway has hitherto been absent. Here we describe the planar polarity phenotypes of loss-of-function and...

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PMID: 9409669
DOI: 10.1242/dev.124.22.4515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Linking Frizzled and Wnt signaling in Drosophila development.PMID 9409669Read ↗

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Interactions between Wingless and DFz2 during Drosophila wing development.Semantic proximity Read ↗

Nonautonomous planar polarity patterning in Drosophila: dishevelled-independent functions of frizzled.Semantic proximity Read ↗

Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism.Semantic proximity Read ↗

Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila.Semantic proximity Read ↗

Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling.Semantic proximity Read ↗

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways.Semantic proximity Read ↗

frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis.Semantic proximity Read ↗

Transducing properties of Drosophila Frizzled proteins.Semantic proximity Read ↗

Non-equivalent roles of Drosophila Frizzled and Dfrizzled2 in embryonic wingless signal transduction.Semantic proximity Read ↗

The role of RhoA in tissue polarity and Frizzled signalling.Semantic proximity Read ↗

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