Article
Non-equivalent roles of Drosophila Frizzled and Dfrizzled2 in embryonic wingless signal transduction.
Current biology : CB - 21 Sept 2000
Moline M M, Dierick H A, Southern C, Bejsovec A
Abstract excerpt
The highly conserved Wnt family of growth factors is essential for generating embryonic pattern in many animal species [1]. In the fruit fly Drosophila, most Wnt-mediated patterning is performed by a single family member, Wingless (Wg), acting through its receptors Frizzled (Fz) and DFrizzled2 (Dfz2). In the ventral embryonic epidermis, Wg signaling generates two different cell-fate decisions: the production of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.