Article
Interactions between Wingless and DFz2 during Drosophila wing development.
Development (Cambridge, England) - 1 Aug 1998
Zhang J, Carthew R W
Abstract excerpt
Drosophila Wingless (Wg) is a secreted signaling protein of the Wnt family. Mutations in the wg gene disrupt the patterning of embryonic segments and their adult derivatives. Wg protein has been shown in cell culture to functionally interact with DFz2, a receptor that is structurally related to the tissue polarity protein Frizzled (Fz). However, it has not been determined if DFz2 functions in the Wg signaling...
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