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Article

Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism.

Genetics - 1 Dec 2005

Povelones Michael, Howes Rob, Fish Matt, Nusse Roel

Abstract excerpt

The frizzled (fz) gene in Drosophila controls two distinct signaling pathways: it directs the planar cell polarization (PCP) of epithelia and it regulates cell fate decisions through Armadillo (Arm) by acting as a receptor for the Wnt protein Wingless (Wg). With the exception of dishevelled (dsh), the genes functioning in these two pathways are distinct. We have taken a genetic approach, based on a series of new...

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Identifiers

PMID: 16085697
DOI: 10.1534/genetics.105.045245
PMCID: PMC1456092

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism.PMID 16085697Read ↗

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