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Article

Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila.

Development (Cambridge, England) - 1 Dec 1999

Chen C M, Struhl G

Abstract excerpt

Wingless (Wg) protein is a founding member of the Wnt family of secreted proteins which have profound organizing roles in animal development. Two members of the Frizzled (Fz) family of seven-pass transmembrane proteins, Drosophila Fz and Fz2, can bind Wg and are candidate Wg receptors. However, null mutations of the fz gene have little effect on Wg signal transduction and the lack of mutations in the fz2 gene has...

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Identifiers

PMID: 10556068
DOI: 10.1242/dev.126.23.5441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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