Article
frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis.
Cell - 23 Dec 1998
Bhat K M
Abstract excerpt
The Drosophila Frizzled (Fz) and Frizzled2 (DFz2) proteins function as receptors for Wingless (Wg) in tissue culture cells. While previous results indicate that loss of function for fz has tissue polarity defects, loss-of-function effects of Dfz2 are not known. Here, we have examined the requirem...
Topics
- Alleles
- Animals
- Bacterial Proteins
- Body Patterning
- Cell Lineage
- Central Nervous System
- Drosophila Proteins
- Drosophila melanogaster
- Epistasis, Genetic
- Frizzled Receptors
- Homeodomain Proteins
- Immunohistochemistry
- Membrane Proteins
- Neurons
- Penetrance
- Phenotype
- Proto-Oncogene Proteins
- Receptors, Cell Surface