Article
Nonautonomous planar polarity patterning in Drosophila: dishevelled-independent functions of frizzled.
Developmental cell - 1 Dec 2002
Strutt Helen, Strutt David
Abstract excerpt
The frizzled (fz) gene of Drosophila is required for planar polarity establishment in the adult cuticle, acting both cell autonomously and nonautonomously. We demonstrate that these two activities of fz in planar polarity are temporally separable in both the eye and wing. The nonautonomous function is dishevelled (dsh) independent, and its loss results in polarity phenotypes that resemble those seen for mutations...
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