Article
Allelotype analysis in the evolution of chronic myelocytic leukemia.
Blood - 1 Sept 1997
Mori N, Morosetti R, Lee S, Spira S, Ben-Yehuda D, Schiller G, Landolfi R, Mizoguchi H, Koeffler H P
Abstract excerpt
To elucidate the genetic events that may play important roles in the progression of chronic myelocytic leukemia (CML), we performed allelotype analysis in 30 patients with CML as the disease transformed to accelerated phase or blast crisis (21 myeloid and 9 lymphoid cases). DNAs were extracted from slides of bone marrow smears or from freshly isolated bone marrow mononuclear cells. The DNAs from the same...
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