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Allelotype analysis in relapsed childhood acute lymphoblastic leukemia.

Oncogene - 9 Oct 2003

Takeuchi Seisho, Seriu Taku, van Dongen Jacques J M, Szczepański Tomasz, Tsukasaki Kunihiro, Takeuchi Naoko, Fermin Anthony C, Seo Hiromi, Bartram Claus R, Koeffler H Phillip

Abstract excerpt

We performed for the first time the allelotype of relapsed childhood acute lymphoblastic leukemia (ALL). A total of 38 cases were screened for loss of heterozygosity (LOH) using 71 markers. In all, 26 (68%) patients showed LOH on at least one chromosomal arm, indicating that LOH is a frequent event at relapse. The most frequent loss was found on chromosomal arm 9p at the p16/INK4a locus (39%). LOH at the TEL gene...

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PMID: 14534546
DOI: 10.1038/sj.onc.1206974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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