Article
Allelotyping in B-cell chronic lymphocytic leukemia (B-CLL).
Leukemia & lymphoma - 1 May 2004
Novak Urban, Tobler Andreas, Fey Martin F
Abstract excerpt
B-cell chronic lymphocytic leukemia (B-CLL) is a heterogeneous malignant disease, both in terms of molecular abnormalities and clinical course. The most frequent chromosomal aberrations in B-CLL are deletions on 13q, 11q, and 17p, and trisomy 12, all of which are of prognostic significance. These aberrations can be detected by conventional cytogenetic analysis and fluorescence in situ hybridization (FISH), but...
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