Article
Allelotype analysis of the myelodysplastic syndrome.
Leukemia - 1 May 2000
Xie D, Hofmann W K, Mori N, Miller C W, Hoelzer D, Koeffler H P
Abstract excerpt
Myelodysplastic syndromes (MDS) are a group of clonal hematologic disorders found predominantly in the elderly. The molecular mechanisms underlying the development of MDS remain obscure. In order to begin to identify tumor suppressor genes involved in these disorders, we performed a detailed microsatellite allelotype of chromosomal deletions associated with MDS. DNAs from both bone marrow and peripheral blood of...
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