Article
Allelotype analysis of childhood acute lymphoblastic leukemia.
Cancer research - 15 Nov 1995
Takeuchi S, Bartram C R, Wada M, Reiter A, Hatta Y, Seriu T, Lee E, Miller C W, Miyoshi I, Koeffler H P
Abstract excerpt
To identify the genetic events that may play an important role in leukemogenesis of childhood ALL, we report for the first time the allelotyping of childhood ALL. Twenty-four cases of childhood ALL were screened for loss of heterozygosity (LOH) using 101 highly polymorphic microsatellite markers, which are distributed among all autosomal chromosomes. For LOH analysis on both chromosomes 9 and 12, 54 childhood ALL...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
