Article
Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20.
1 Dec 1993
Abstract excerpt
A deletion of the long arm of chromosome 20 [del(20q)] is a recurring abnormality in malignant myeloid disorders. The occurrence of the del(20q) in a broad spectrum of myeloid disorders suggests that the loss of genetic material on 20q could provide a proliferative advantage to myeloid cells, possibly through the loss of a tumor-suppressor gene. We have examined a series of patients with the del(20q) using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.