Article
High-resolution allelotype analysis of childhood B-lineage acute lymphoblastic leukemia.
Leukemia - 1 Jul 1998
Chambon-Pautas C, Cavé H, Gérard B, Guidal-Giroux C, Duval M, Vilmer E, Grandchamp B
Abstract excerpt
Knowledge of the patterns of allelic loss has been useful in identifying tumor suppressor genes in many solid tumors. Although the loss of genetic material in acute lymphoblastic leukemias has been documented by cytogenetic studies and microsatellite typing, a global overview of losses of heterozygosity occurring throughout the genome was not yet available. We have performed a high resolution allelotype analysis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.