High-resolution allelotype analysis of childhood B-lineage acute lymphoblastic leukemia.

doi:10.1038/sj.leu.2401069

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Article

High-resolution allelotype analysis of childhood B-lineage acute lymphoblastic leukemia.

Leukemia - 1 Jul 1998

Chambon-Pautas C, Cavé H, Gérard B, Guidal-Giroux C, Duval M, Vilmer E, Grandchamp B

Abstract excerpt

Knowledge of the patterns of allelic loss has been useful in identifying tumor suppressor genes in many solid tumors. Although the loss of genetic material in acute lymphoblastic leukemias has been documented by cytogenetic studies and microsatellite typing, a global overview of losses of heteroz...

Topics

Alleles
Burkitt Lymphoma
Child
Female
Genetic Markers
Genotype
Humans
Karyotyping
Loss of Heterozygosity
Male
Microsatellite Repeats
Polymerase Chain Reaction
Precursor Cell Lymphoblastic Leukemia-Lymphoma

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