Article
Allelotype analysis of adult T-cell leukemia.
Blood - 15 Sept 1998
Hatta Y, Yamada Y, Tomonaga M, Said J W, Miyosi I, Koeffler H P
Abstract excerpt
Allelotype analysis of adult T-cell leukemia (ATL) was undertaken for the first time to identify chromosomal loci relevant to the development of acute/lymphomatous ATL. Loss of heterozygosity (LOH) was screened using 94 highly polymorphic microsatellite markers, distributed among all nonacrocentric, autosomal chromosomes. In each of the 22 cases, DNA obtained from their leukemic cells in acute/lymphomatous phase...
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