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Article

Relation of age and apolipoprotein E to cognitive function in Down syndrome adults.

Neuroreport - 27 May 1997

Alexander G E, Saunders A M, Szczepanik J, Strassburger T L, Pietrini P, Dani A, Furey M L, Mentis M J, Roses A D, Rapoport S I, Schapiro M B

Abstract excerpt

To test the cognitive effects of aging and apolipoprotein E (APOE) in individuals at high risk for Alzheimer's disease (AD), we assessed APOE genotypes and performance on a battery of neuropsychological tests in 41 non-demented, Down syndrome (DS) adults. Old DS subjects (ages 41-61 years) showed poorer memory and orientation scores than young DS adults (ages 22-38 years), but the groups did not differ in other...

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Source

Identifiers

PMID: 9223061
DOI: 10.1097/00001756-199705260-00009

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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