Article
The role of p53 tumor suppressor gene in human head and neck tumorigenesis.
Acta oto-laryngologica. Supplementum - 1 Jan 1997
Pavelic Z P, Gluckman J L
Abstract excerpt
Molecular genetics has led to new insights into diagnosis and treatment of human cancer. The alterations of tumor suppressor genes like retinoblastoma, p53 and others may have an important role in tumorigenesis. Mutations of p53 have been found in a majority of human malignancies including head and neck cancer. The distribution of p53 is different between types of tumors, suggesting environmental exposure as a...
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