The role of the p53 tumor suppressor gene in squamous cell carcinoma of the head and neck.

doi:10.1001/archotol.1993.01880220064009

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Article

The role of the p53 tumor suppressor gene in squamous cell carcinoma of the head and neck.

Archives of otolaryngology--head & neck surgery - 1 Oct 1993

Field J K, Pavelic Z P, Spandidos D A, Stambrook P J, Jones A S, Gluckman J L

Abstract excerpt

The objective of this review is to determine whether the p53 tumor suppressor gene plays a role in the development of head and neck cancer. Mutations in the p53 tumor suppressor gene have been shown to be one of the most common genetic abnormalities in human cancers, and the published literature...

Topics

Carcinoma, Squamous Cell
Gene Expression Regulation, Neoplastic
Genes, p53
Head and Neck Neoplasms
Humans
Mutation
Prognosis

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